Alnylam was founded in 2002 on a revolutionary vision and bold mission which remain firmly in place today. We are leading the translation of RNA interference (RNAi) into a new class of innovative medicines with the potential to transform the lives of people with rare genetic, cardio-metabolic, hepatic infectious, and central nervous system diseases with unmet need. Our first medicine, the first-ever RNAi therapeutic, has recently been approved by the FDA in the US for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults and by the European Medicines Agency in the EU for the treatment of hATTR amyloidosis in adults with stage 1 or stage 2 polyneuropathy. In addition, Alnylam has four investigational medicines in late-stage development. www.alnylam.com.
This role will be responsible for the establishment and execution of Alnylam’s operations in the countries. The General Manager will develop and execute the go to market strategy across multiple products, building and maintaining a high performing cross-functional organization within the countries. The GM will ensure exceptional commercial, financial and compliance performance of the country organizations; build Alnylam’s reputation for delivering value to patients, healthcare system stakeholders and society in the countries; ensure Alnylam’s local team contributes effectively to Alnylam’s cross-functional goals (e.g. trial enrollment); and build an organization that is passionate, engaged, and feels strongly connected to the Company culture and values.
This role will report to the SVP Regional Head, Europe, Middle East and Africa & Canada (CEMEA) and will be a member of the Regional Management Team.
Summary of Key Responsibilities
Build and lead a high performing cross-functional country organization in both Spain & Portugal
Design local go-to-market strategy for Alnylam’s portfolio, ensure high quality execution and successful launch of multiple products
Customer and healthcare stakeholder engagement
Appropriate solutions to optimize the value of Alnylam’s medicines for patients and stakeholders
Pricing and access strategy and execution, including innovative value propositions
Ensure strong commercial and financial performance including effective forecasting and planning and appropriate resourcing of key activities across the organization
Ensure effective distribution solutions within the countries to bridge from Alnylam’s global supply chain to patients
As Alnylam’s responsible legal representative in the countries, ensure flawless compliance with country regulations and company policy, including healthcare compliance, financial controls, pharmacovigilance and other legal obligations.
Ensure strong cross-functional integration within the country organizations at the level of product teams, field force and country management team
Collaborate with global and regional functional leaders and provide matrix oversight to Medical affairs, Finance, HR and Legal staff
Work within Alnylam Network operating model to:
Ensure strong product strategy alignment with the regional and global team and other countries
Via the regional marketing, access and commercial (MAC) teams, provide high quality input to the global MAC and program teams, to ensure that trial design meets country access needs, to ensure that global product strategies and tactics are appropriate for the countries, and to help assess early stage product opportunities
Collaborate with partners as appropriate to optimize performance
Clear alignment with Alnylam Core Values: Commitment to People; Innovation and Discovery; Sense of Urgency; Open Culture; Passion for Excellence
Strong general business and financial acumen. Solid local network.
Outstanding Commercial understanding of the local market, including orphan drugs commercialization and development of local solutions to optimize the value of a medicine
Demonstrated ability to lead and engage on Market Access in the country, including developing stakeholder relationships and negotiating effectively
Outstanding strategic thinking, across the entire spectrum of the business
Engaging leader, able to attract and develop top talent and inspire and align a diverse organization
Organizational flexibility: Outstanding listening skills; comfortable operating and influencing in all directions in a global network/matrix environment
Execution leadership, demonstrated ability and drive to ensure outstanding performance by all staff across all functions
A proven career in the biopharmaceutical commercial industry including at significant experience in the Spain and Portugal
Demonstrated leadership as General Manager, including international matrix leadership and full P&L responsibility
Success in building teams and in launching new products in Rare Diseases is essential
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